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Dr Greg Scutt

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Dr Greg Scutt

Greg Scutt graduated from the University of Bath with a BPharm in 1999 and registered as a pharmacist after a pre-reg at King’s College Hospital (KCH) in 2000. Greg is currently Principal Clinical Lecturer, and academic head of the Brighton and Sussex Centre for Medicines Optimisation – a joint venture between the 九色视频 and Brighton and Sussex University Hospitals NHS Trust.

Greg-Scutt

How I like to teach

I currently lecture on the MPharm degree in areas that include neurodegeneration, epilepsy, hepatology, pharmacokinetics, and clinical pharmacy. The material I lecture spans both the fundamental pharmacology through to clinical pharmacy and therapeutics. I am module leader for the MPharm 4 module preparing for practice which leads our students through the transition from student to pre-registration pharmacist.

I believe that understanding the mechanics of a concept aids learning, and so I take this approach during my lectures.

There's a big difference between knowing the name of something and knowing something

Richard Feynman

My research interests

Through my research in the BSCMO I run projects that span both the laboratory and the clinic. I use a scientific approach to help understand how medicines work, how they cause harm, and how they can be used more safely and effectively. In particular I am interested in why variation exists in regards to efficacy and adverse effects, and how this can be explained by genomic variation.

My PhD was in the area of neuroscience and ageing. During this work I used a number of electrophysiology techniques to understand changes that occur during ageing in a neurone that controls feeding, and learning and memory in the CNS of a model system (Lymnaea stagnalis). This model system is a useful tool to examine age-related changes to learning and memory using a top-down, systems level approach, and raises interesting questions about the mechanisms that underlie cognitive decline in humans. I continue to have an interest in this area and supervise several undergraduate students on projects related to ageing, and ageing of the central nervous system.

Research activity

Current research projects:

  • The role of genotype in antidepressant response in older people (Better targeting of antidepressants in older people)
  • Do Nrf2/Keap1 polymorphisms determine ADR rates in older people (The ADR gene study)
  • Changes to Nrf2/Keap1 expression during ageing in humans
  • What is the mechanism through which antipsychotics cause metabolic syndrome and induces beta cell toxicity?

Previous research projects:

  • Changes to excitability in a modulatory neurone that controls feeding and learning and memory during ageing.

Research Centres and Groups

  • Brighton and Sussex Centre for Medicines Optimisation
  • Centre for Stress and Age-Related Disease (STRAND)

Social media

Contact me

Dr Greg Scutt
Clinical Principal Lecturer

Pharmacy and Biomolecular Sciences
708 Huxley Building
Moulsecoomb
Brighton
BN2 4GJ

Email: G.Scutt@brighton.ac.uk

Biography

I graduated from the University of Bath in 1999 and registered as a pharmacist after a pre-reg at King’s College Hospital (KCH) in 2000. I then worked for several years at KCH first as a Basic Grade Pharmacist, and then as a Senior Pharmacist in Clinical Services Pharmacist with an interest in care of older people. During this time obtained a certificate in pharmacy practice from the University of London, and a Diploma in Clinical Pharmacy Practice from the 九色视频. I then moved to Brighton and Sussex University Hospitals (BSUH) and the 九色视频 as a Clinical Lecturer, providing care to older people at BSUH, and lecturing in the School of Pharmacy and Biomolecular Sciences under the mentorship of Prof Graham Davies. During this time I studied for a PhD in neuroscience at the 九色视频 (supervised by Drs Mark Yeoman and Marcus Allen). The research looked and changes in neuronal excitability during the ageing process. 

In 2013, I took up a new role as head of the Brighton and Sussex Centre for Medicines Optimisation, a joint venture between the 九色视频 and Brighton and Sussex University Hospitals NHS Trust. Through this role I am keen to promote the clinical science research and clinical education as key elements of clinical pharmacists’ portfolio. I believe that clinical pharmacists are in an excellent position to identify medicines related research questions, and through clinical science research improve our understanding of how medicines can be used more safely and effectively to improve patient care.

Research output

PhD students

 
NameThesis
Madeleine Honey (2016 - current) What is the mechanism through which antipsychotics cause metabolic syndrome and induces beta cell toxicity? 
Lamia Hachoumi (2014 - current) Role of inflammation in CNS ageing in the pond snail, Lymnaea 
Jawza Alsabhan (2015 - current) Role of BDNF in Alzheimer’s Disease 

Roles

Module Leader: Preparing for Pharmacy Practice

Academic Head: Brighton and Sussex Centre for Medicines Optimisation
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Lewes Road
Brighton
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